Predicting Response To Platinum Chemotherapy Via Marker Of DNA Damage

 

 

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Predicting Response To Platinum Chemotherapy Via Marker Of DNA Damage

via Ask a Health Expert by www.medicalnewstoday.com on 3/24/12

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Scientists have uncovered a marker of DNA damage that could predict who will respond to platinum-based chemotherapy drugs like cisplatin or carboplatin. These drugs are widely used for ovarian cancer, but as with most cancer drugs, it can be difficult to predict who will respond to therapy. A team of researchers from the Dana-Farber Cancer Institute found that this marker, telomeric allelic imbalance or tAI, could predict sensitivity to therapy in patients with triple-negative breast cancer...

 

 

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Employing Bronchoscopy To Guide Effective Treatment For Refractory Asthma

 

 

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Employing Bronchoscopy To Guide Effective Treatment For Refractory Asthma

via Ask a Health Expert by www.medicalnewstoday.com on 3/24/12

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Using a bronchoscope to visually examine the airways and collect fluid and tissue can help guide effective therapy for difficult-to-treat asthma patients, according to researchers at National Jewish Health. Reporting in the March 2012 issue of the journal Chest, the researchers identified five distinct phenotypes among the refractory asthma patients, and successfully treated four of them, often with reduced asthma medications...

 

 

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Discovery Of Genetic Mutation In Familial Chronic Diarrhea Syndrome

 

 

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Discovery Of Genetic Mutation In Familial Chronic Diarrhea Syndrome

via Ask a Health Expert by www.medicalnewstoday.com on 3/24/12

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When the intestines are not able to properly process our diet, a variety of disorders can develop, with chronic diarrhea as a common symptom. Chronic diarrhea can also be inherited, most commonly through conditions with genetic components such as irritable bowel syndrome. Researchers in Norway, India, and at the HudsonAlpha Institute for Biotechnology have identified one heritable DNA mutation that leads to chronic diarrhea and bowel inflammation. Shawn Levy, Ph.D...

 

 

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Risk For Early Alcohol Use Reduced By Middle School Teacher Support

 

 

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Risk For Early Alcohol Use Reduced By Middle School Teacher Support

via Ask a Health Expert by www.medicalnewstoday.com on 3/24/12

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Anxiety, depression, stress and social support can predict early alcohol and illicit drug use in youth, according to a study from Carolyn McCarty, PhD, of Seattle Children's Research Institute, and researchers from the University of Washington and Seattle University. Middle school students from the sixth to the eighth grade who felt more emotional support from teachers reported a delay in alcohol and other illicit substance initiation. Those who reported higher levels of separation anxiety from their parents were also at decreased risk for early alcohol use...

 

 

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Worm Model Of Back-Up Telomere Repair Strategy Could Speed Identification Of...

 

 

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Worm Model Of Back-Up Telomere Repair Strategy Could Speed Identification Of Anti-Cancer Drugs

via Ask a Health Expert by www.medicalnewstoday.com on 3/24/12

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Rapidly dividing cancer cells are skilled at patching up damage that would stop normal cells in their tracks, including wear and tear of telomeres, the protective caps at the end of each chromosome. Loss of telomeres forces cells out of the dividing game and into a growth arrest state called "senescence," but cancer cells evade this by employing an enzyme called telomerase to extend eroded telomeres. If telomerase fails to activate, the tumor cells of about 10 percent of all human cancers have a back-up strategy to build serviceable telomeres and keep dividing...

 

 

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Low-Dose Daily Aspirin Enough to Help Heart Attack Patients: Study

 

 

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Low-Dose Daily Aspirin Enough to Help Heart Attack Patients: Study

via Ask a Health Expert by http://news.yahoo.com/medications-drugs on 3/24/12

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SATURDAY, March 24 (HealthDay News) -- Heart attack patients who take either a high or low dose of aspirin daily have the same level of protection against another heart attack or other cardiovascular events such as stroke, according to a new study.

 

 

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Stem cell therapy could repair some heart damage

Stem cell therapy could repair some heart damage:
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Patients with advanced heart disease who received an experimental stem cell therapy showed slight improvements in blood pumping but no change in most of their symptoms, US researchers said Saturday.